Vitamin D Receptor Gene Fok1 Polymorphism Predicts Calcium Absorption and Bone Mineral Density in Children
نویسندگان
چکیده
منابع مشابه
Bone mineral density in relation to polymorphism at the vitamin D receptor gene locus.
Polymorphism at the vitamin D receptor gene was examined in relation to bone mineral density (BMD) at spine, femur, and forearm in 86 monozygotic (MZ) and 39 dizygotic (DZ) adult female twins. All were white, 63 pairs (44 MZ, 19 DZ) were premenopausal, and 43 pairs (31 MZ, 12 DZ) were discordant for age at menopause or use of estrogen. Each individual of the DZ pairs and one individual of MZ pa...
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objective: osteoporosis is a bone disorder that reduces bone mineral density (bmd) and leads to bone fracture. in addition to different factors, gene polymorphisms have been revealed to be associated with osteoporosis. in this study, we investigated the association between the bsmi polymorphism of vitamin d receptor (vdr) gene (rs1544410) and bmd in a population of iranian women. materials and ...
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OBJECTIVE Bone mineral density (BMD) in adolescence is under strong genetic control. The calcium sensing receptor (CASR) is involved in the regulation of calcium homeostasis and bone resorption. The A986S polymorphism of the CASR has recently been associated with serum calcium levels, in one hitherto unconfirmed report. We investigated whether this polymorphism was related to BMD, circulating c...
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OBJECTIVE Parathyroid hormone (PTH) and vitamin D are the most important hormones regulating calcium metabolism. In primary hyperparathyroidism (PHPT) excessive amounts of PTH are produced. Bone turnover is enhanced, leading to reduced bone mineral density and elevated levels of serum calcium. The aim of this study was to investigate relations between serum levels of 25-hydroxyvitamin D (25(OH)...
متن کاملVitamin D receptor gene, biochemical bone markers and bone mineral density in Mexican women on dialysis.
BACKGROUND The influence of the Bsm1 polymorphism of the vitamin D receptor (VDR) gene on mineral and bone disorders in chronic kidney disease (CKD) is still under discussion. The aim of this study was to analyse the relationship between VDR polymorphism, bone mineral density (BMD), biochemical bone markers and clinical factors in women on peritoneal dialysis (PD) and haemodialysis (HD). METH...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 1999
ISSN: 0884-0431
DOI: 10.1359/jbmr.1999.14.5.740